Drug-Drug & Drug-Lifestyle Interaction Engine
Scoped and led the end-to-end build of a drug-drug interaction (DDI) and drug-lifestyle interaction (DLI) database, covering alcohol, tobacco, and food as lifestyle parameters.
The tool enables multi-product interaction checks with severity grading (life-threatening, severe, moderate, mild, no interaction), layered explanations, and user-facing action recommendations.
Collaborated with teams to define schema, severity logic, consume-type mapping, and front-end display architecture.
Extended the database to cover oncology-specific interactions in partnership with Tata Memorial Centre (TMC), and integrated into hospital EMR systems.
The Challenge
- No standardised interaction database existed internally.
- Over 5.5 lakh raw interactions from various sources needed to be cleaned, classified and mapped to Tata 1mg's internal drug IDs across drugs and products.
- FDC (fixed-dose combination) interactions required a novel logic framework, as standard interaction tools do not account for combination drug behaviour.
- Oncology drug interactions required a separate pipeline due to their high risk, highly specific nature and the involvement of an external hospital partner.
The Approach & Solution
- Used Python and scrapers to structure data across 5.5 lakh interaction entries, building a phased delivery pipeline across severity tiers.
- Designed a consume-type level mapping system to enable interaction checks at the granular drug-form level, not just the salt level.
- Built interaction libraries for red (life-threatening/severe), yellow (moderate), blue (mild), and green (no interaction) categories, each with severity grading, explanations, and layman-friendly action text.
- Led reference mapping for ~200K DDI entries and ~1,000 DLI entries to anchor every interaction to a citable clinical source.
- Collaborated with the Tata Memorial Centre to isolate and deliver oncology-specific interactions (~31,000 interactions) with specialised validation.
Key Results & Commercial Impact
Technology Stack & Tools
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